Panbesy is the brand name adopted in Singapore (by Eurodrug Laboratories) for the appetite suppressant Phentermine. This drug belongs to the pharmacological category of phenethylamines and amphetamines.
Panbesy was approved to assist with weight reduction in overweight patients for short term usage, and it is meant to be combined with lifestyle changes. Normally, it is prescribed to people whose health is at risk because of their weight.
Phentermine is an active ingredient that is distributed and manufactured in several countries under various brand, trade and generic names. For instance: Ionamin (Celltech), Adipex-P (Teva), Phentermine (Eon Labs), Fastin (GlaxoSmithKline), Acxion (Investigacion Farmaceutica), Phentermine (KVK-TECH), etc. In some countries (like Canada, the USA and Australia), this drug is classed as a controlled substance, as it can be addictive.
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Panbesy works on the neurotransmitters of your brain. This is a central stimulant drug and a methamphetamine isomer. It stimulates your neurons to release a specific neurotransmitter group called catecholamines, amongst which are adrenaline (also called epinephrine), norepinephrine and dopamine.
These compounds are able to suppress your appetite because of the way they act on your central nervous system. This process shares similarities with other appetite suppressant stimulants, like phendimetrazine and diethylpropion. The neurotransmitters convey the alert response that halts the hunger.
Panbesy is utilised to lower body weight in overweight or obese patients. Frequently, it prescribed as part of a weight reduction regimen based on behavioural modification. Generally, it is employed to manage exogenous obesity in overweight or obese patients who have additional risk factors, such as diabetes, hypertension and hyperlipidemia. This drug functions by directly impacting the region of the brain which controls the appetite, causing you to feel fuller.
Administration and Dosage
Patients are advised to take Panbesy for only short term periods (normally around twelve weeks). This should be combined with other non pharmacological weight loss strategies, like exercise and healthy dieting. Because of the insomnia risks, it is advisable to take Panbesy prior to breakfast, or one to two hours afterwards.
Mostly, Panbesy is well tolerated, although it can produce some side-effects as it releases catecholamines. Amongst the most commonly seen effects are: elevated blood pressure, tachycardia (increased heart rate), nervousness, palpitations, insomnia and irritability. Furthermore, if this medication is consumed over the long term, it might cause addiction and euphoria.
Less frequently seen side-effects are alterations in sex drive, blurred vision, confusion, clumsiness, dizziness, diarrhoea, headache, dry mouth, vomiting or nausea, irregular heartbeat, itching or skin rash, psychosis, fatigue, bad taste and stomach pain.
Panbesy should be avoided whenever:
- Patients are allergic to any phentermine ingredient in pharmaceutical form (normally tablets or capsules), or to any other sympathomimetic (like pseudoephedrine).
- Patients have taken fenfluramine, guanethidine, dexfenfluramine, guanadrel or furazolidone, or any MAOIs (mono amine oxidase inhibitors), like phenelzine, over the past two weeks.
- Patients have moderate hyperthyroidism, high blood pressure, circulatory or heart disease, serious blood vessel narrowing, or glaucoma.
- Patients have a history of drug or alcohol abuse, or are agitated.